MASCC now recommends PBM Therapy for the treatment of oral mucositis.
The MASCC has recently announced PBM as the recommended treatment for OM based upon 24 studies evaluating the effects. “The evidence supported the development of 2 new guidelines: a recommendation in favor of PBM for the prevention of oral mucositis in patients receiving high-dose chemotherapy for HSCT with or without total body irradiation, and a suggestion for PBM in the prevention of oral mucositis in patients receiving H&NRT without concomitant chemotherapy.”
What is Mucositis?
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. Mucositis can occur anywhere along the gastrointestinal tract, but oral mucositis refers to the particular inflammation and ulceration that occurs in the mouth. Oral mucositis is a common and often debilitating complication of cancer treatment.
“500,000 cases of OM per year,
Medicare reimbursed $40K per person”
Annette Quinn, RN, MSN
University of Pittsburg Cancer Center
Clinical Studies
Effects of PBM on Oral Mucositis:
SPECIAL ARTICLE:
Systematic review of PBM for the managementof oral mucositis in cancer patients and clinical practice guidelines:
Effective in reducing the severity of chemoradiotherapy-induced OM
Study Location:
Department of Oral Medicine (Oral Pathology), Dental School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Author Information:
Oton-Leite AF1, Silva GB, Morais MO, Silva TA, Leles CR, Valadares MC, Pinezi JC, Batista AC, Mendonça EF.
CONCLUSIONS:
These findings demonstrated that PBM was effective in reducing the severity of chemoradiotherapy-induced OM and was associated with the reduction of inflammation and repair.
Efficacy of PBM for treatment of cancer oral mucositis: a systematic review and meta-analysis
Study Location:
Graduation Program on Evaluation and Production of Technologies for the Brazilian National Health System, Hospital Nossa Senhora da Conceição, Porto Alegre, Rio Grande do Sul, Brazil.
Author Information:
Anschau F, Webster J, Capra MEZ, de Azeredo da Silva ALF, Stein AT.
CONCLUSIONS:
PBM demonstrates potential for decreasing the resolution time of OM lesions by approximately 4.21 days.
Preventive PBM in HNSCC patients receiving chemoradiotherapy is an effective tool for reducing the incidence of grade 3-4 OM
Study Location:
Coordination of Clinical Research, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil.
Author Information:
Antunes HS1, Herchenhorn D, Small IA, Araújo CM, Viégas CM, Cabral E, Rampini MP, Rodrigues PC, Silva TG, Ferreira EM, Dias FL, Ferreira CG.
CONCLUSION:
Preventive PBM in HNSCC patients receiving chemoradiotherapy is an effective tool for reducing the incidence of grade 3-4 OM. Efficacy data were corroborated by improvements seen in quality of life.
PBM was effective in improving the patient’s subjective experience of OM and QOL in HNC patients receiving CRT.
Study Location:
Department of Radiotherapy and Oncology, Kasturba Medical College and Hospital, Manipal University, Manipal, Karnataka, India.
Author Information:
Gautam AP1, Fernandes DJ, Vidyasagar MS, Maiya AG, Nigudgis.
CONCLUSIONS:
PBM was effective in improving the patient’s subjective experience of OM and QOL in HNC patients receiving CRT.
How does Photon Beam Therapy relieve the pain of Mucositis?
For more information and/or to schedule a demonstration please call:
+1-843-716-5300
EMAIL: info@curalase.comPhoton Beam Therapy in the News
New Guidelines Published for Oral Mucositis Relief
July 16, 2019
Researchers and clinicians from around the world have issued new guidelines for the treatment of oral mucositis in Supportive Care in Cancer that involve photobiomodulation therapy, a form of light therapy.
Light therapy could replace opioids as main treatment for cancer treatment side effect
July 9, 2019
A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy.