Mucositis

MASCC now recommend PBM Therapy for the treatment of oral mucositis.

The Multinational Association of Supportive Care in Cancer (MASCC) now recommend PBM Therapy for the treatment of oral mucositis in patients with high-dose chemotherapy.

What is Mucositis?

Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. Mucositis can occur anywhere along the gastrointestinal tract, but oral mucositis refers to the particular inflammation and ulceration that occurs in the mouth. Oral mucositis is a common and often debilitating complication of cancer treatment.

600,000 Chemo treatments per year
$40K per person just to treat Mucusitis

The CuraLase Digest of Clinical Studies

Studies about the effects of Photon Therapy on Oral Mucusitis:

“Effective in reducing the severity of chemoradiotherapy-induced OM”

Study Location:
Department of Oral Medicine (Oral Pathology), Dental School, Federal University of Goiás, Goiânia, Goiás, 74605-220, Brazil.
Author Information:
Oton-Leite AF1, Silva GB, Morais MO, Silva TA, Leles CR, Valadares MC, Pinezi JC, Batista AC, Mendonça EF.

CONCLUSIONS:
These findings demonstrated that LLLT was effective in reducing the severity of chemoradiotherapy-induced OM and was associated with the reduction of inflammation and repair.

https://www.ncbi.nlm.nih.gov/pubmed/?term=25824475
“Photon Therapy decreased the severity of OM and oral pain in elderly HNC patients”

Study Location:
Department of Radiotherapy and Oncology, Kasturba Medical College and Hospital, Manipal University, Manipal, Karnataka, India; Department of Physiotherapy, Manipal College of Allied Health Sciences, Manipal University, Manipal, Karnataka, India.
Author Information:
Gautam AP1, Fernandes DJ2, Vidyasagar MS3, Maiya AG4, Guddattu V5.

CONCLUSIONS:
Photon Therapy decreased the severity of OM and oral pain in elderly HNC patients.

https://www.ncbi.nlm.nih.gov/pubmed/?term=25704314
“Preventive Photon Therapy in HNSCC patients receiving chemoradiotherapy is an effective tool for reducing the incidence of grade 3-4 OM”

Study Location:
Coordination of Clinical Research, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil.
Author Information:
Antunes HS1, Herchenhorn D, Small IA, Araújo CM, Viégas CM, Cabral E, Rampini MP, Rodrigues PC, Silva TG, Ferreira EM, Dias FL, Ferreira CG.

CONCLUSION:
Preventive Photon Therapy in HNSCC patients receiving chemoradiotherapy is an effective tool for reducing the incidence of grade 3-4 OM. Efficacy data were corroborated by improvements seen in quality of life.

https://www.ncbi.nlm.nih.gov/pubmed/?term=24044799
“Photon Therapy was effective in improving the patient’s subjective experience of OM and QOL in HNC patients receiving CRT.”

Study Location:
Department of Radiotherapy and Oncology, Kasturba Medical College and Hospital, Manipal University, Manipal, Karnataka, India.
Author Information:
Gautam AP1, Fernandes DJ, Vidyasagar MS, Maiya AG, Nigudgis.

CONCLUSIONS:
Photon Therapy was effective in improving the patient’s subjective experience of OM and QOL in HNC patients receiving CRT.

https://www.ncbi.nlm.nih.gov/pubmed/?term=23224689

How does Photon Therapy relieves the pain of Oral Mucositis?

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